In a statement published on Telegram, the ministry said Ukraine "multiplied the number of unilateral attacks using drones and artillery shells on the energy infrastructure of Russian regions".
It said the strikes had caused damage in Russia's Bryansk, Belgorod, Smolensk, Lipetsk and Voronezh regions as well as the Ukrainian regions of Luhansk and Kherson - parts of which Russia controls.
Reuters was unable to verify the reports of the strikes.
In its own statement on Telegram, Ukraine's military said that the reports were fake and that its forces were only striking military targets.
Ukraine's military has previously said it halted strikes on Russian energy facilities on March 18.
Russia and Ukraine agreed last month to a US proposal for a 30-day moratorium on striking each other's energy infrastructure.
Both sides have since repeatedly accused each other of violating the deal.
The deal was part of a wider diplomatic push by US President Donald Trump since his return to office in January to end the conflict.
Separately on Saturday, authorities in two Russian regions reported Ukrainian drone strikes on local industrial facilities.
The governor of Russia's Volga river region of Mordovia said Ukrainian drones had struck an industrial facility.
Media reports said it was an optical fibre factory in the region's capital, Saransk.
The governor of Samara region, another Volga riverside province, said that a factory in the city of Chapaevsk had been attacked by Ukrainian drones.
A source in Ukraine's SBU security service told Reuters that the target was a plant producing industrial explosives, and that the strike had caused multiple explosions and fires.
On Friday, a Russian strike on the Ukrainian city of Kryvyi Rih killed at least 19 people, including nine children, local officials said.
Russia's defence ministry said it targeted a military gathering in the city, a statement the Ukrainian military denounced as disinformation.
Kryvyi Rih is the hometown of Ukrainian President Volodymyr Zelenskiy.
"The missile struck an area right next to residential buildings - hitting a playground and ordinary streets," Zelenskiy wrote on Telegram.
Zelenskiy blamed the daily strikes on Russia's unwillingness to end the war: "Every missile, every drone strike proves Russia wants only war," he said, urging Ukraine's allies to increase pressure on Russia and bolster Ukraine's air defences.
with AP
