The Queen of Pop worked with Price on her acclaimed 2005 record Confessions On A Â Dance Floor as well as her recent Celebration Tour and the pair will be collaborating in the studio once again as the Material Girl hitmaker plots her first album since 2019's Madame X.
A source told The Sun newspaper's Bizarre column: "Stuart was credited with helping Madonna return to form with their Confessions album, so for her to start working again with him is hugely exciting.
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"That record was incredible and Madonna is excited about what they can come up with.
"It has been five years since she released Madame X, which was a concept album and Madonna is ready to put down some new tunes.
"Working with Stu on her tour reignited the spark. She has fire in her belly and cannot wait to get started."
The 66-year-old singer confirmed she was working with Price at his home studio in London through a series of posts on Instagram - where she also shared snaps of herself and boyfriend Akeem Morris cheering Chelsea to victory in their Premier League clash with Brighton at Stamford Bridge at the weekend.
Price revealed last year how the singer had convinced him to get involved in her Celebration Tour that marked her 40 years in music.
He said: "When she announced the greatest hits tour I called her just to say, 'Congratulations, I think this is a great idea.'
"And she said, 'I was just thinking about you, and I thought you'd be the perfect person to work with on this.'
"So two weeks later, I went to New York."
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